Several years ago, I *had* to give up on Intel mobos, mainly for the reasons of the lack of certain higher-end features, timeliness to market with new designs, and general availability.
To be fair, that was back in the mid-90s. At that point in time, I had been dabbling in still-expensive Supermicro mobos. But, the price for Supermicro product began to ameliorate about that same time, so, I switched over to Supermicro product for my primary project mobo and still use Super-O today.
As for AMD product -- never had a problem with their microprocessors, just a lot of the cheesy mobos that they got plugged into and the chipsets on many of those mobos, namely SiS and Via.